Name | D-Gluconic acid, copper(II)salt |
Synonyms | CUPRIC GLUCONATE Copper gluconate COPPER GLUCONATE COPPER(II) GLUCONATE Copper(II) gluconate copper di-D-gluconate COPPER(+2)D-GLUCONATE bis(d-gluconato)-coppe COPPER(II) D-GLUCONATE Chelates of copper gluconate GLUCONIC ACID COPPER(II) SALT D-Gluconic acid, copper(II)salt D-Gluconic acid copper(II) salt D-GLUCONIC ACID, COPPER(II) SALT bis[[(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoyl]oxy]copper |
CAS | 527-09-3 |
EINECS | 208-408-2 |
InChI | InChI=1/2C6H12O7.Cu/c2*7-1-2(8)3(9)4(10)5(11)6(12)13;/h2*2-5,7-11H,1H2,(H,12,13);/q;;+2/p-2/t2*2-,3-,4+,5-;/m11./s1/rC12H22CuO14/c14-1-3(16)5(18)7(20)9(22)11(24)26-13-27-12(25)10(23)8(21)6(19)4(17)2-15/h3-10,14-23H,1-2H2/t3-,4-,5-,6-,7+,8+,9-,10-/m1/s1 |
Molecular Formula | C12H22CuO14 |
Molar Mass | 453.84 |
Density | 1.777[at 20℃] |
Melting Point | 155-157°C(lit.) |
Boling Point | 673.6℃[at 101 325 Pa] |
Water Solubility | slightly soluble |
Solubility | Aqueous Acid (Slightly), Water (Sparingly, Sonicated) |
Vapor Presure | 13.3Pa at 20℃ |
Appearance | powder |
Color | Light Blue to Blue |
Exposure Limit | ACGIH: TWA 1 mg/m3NIOSH: IDLH 100 mg/m3; TWA 1 mg/m3 |
Merck | 14,2640 |
Storage Condition | Inert atmosphere,Room Temperature |
Stability | Hygrscopic |
Refractive Index | 16.5 ° (C=1, H2O) |
MDL | MFCD00075297 |
Physical and Chemical Properties | Melting point 155-157°C water-soluble easily soluble |
Use | Used as food additives, pharmaceutical raw materials |
Safety Description | 24/25 - Avoid contact with skin and eyes. |
WGK Germany | 3 |
RTECS | LZ5058000 |
TSCA | Yes |
HS Code | 29181600 |
Raw Materials | Copper(II) sulfate Calcium Gluconate |
LogP | -2.98 |
EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
introduction | copper gluconate is a fine copper light blue powder. The FAO/WHO Expert Committee on Food Additives (JECFA) evaluated copper gluconate as a "useful, safe and necessary" copper supplement. At present, the United States, Japan and other countries have designated copper gluconate as a permitted food fortifier and as a treatment for copper deficiency. |
use | copper gluconate (copper Gluconate) is a form of copper health care products, commonly used in beauty cosmetics and skin care products. It can also be used to treat diseases such as copper deficiency that cause anemia. Nutritional supplements. According to Japanese regulations, it is allowed to be used for fortified copper in milk substitute products, and the copper content of milk substitute drinks with standard milk concentration per liter shall not exceed 0.6mg. Used as food additive and pharmaceutical raw material |
content analysis | accurately weigh about 1.5g of the sample, dissolve it in 100ml of water in a 250ml conical flask, add 2ml of glacial acetic acid and 5g of potassium iodide, mix it evenly, and titrate it with 0.1mol/L sodium thiosulfate to light yellow. Add 2g ammonium thiocyanate, mix well, add 3ml starch test solution (TS-235) and continue titration to milky white end point. Sodium thiosulfate is equivalent to copper gluconate (C12H22 CuO14)45.38mg per Ml0.1mol/L. |
toxicity | GRAS(FDA,§ 182.5260,2000). |
use limit | is limited to GMP (FDA,§ 184.1260,2000). |
production method | is obtained by crystallization of gluconic acid and copper oxide. It is obtained by the reaction and crystallization of gluconate and copper salt. It is crystallized by the reaction of sodium gluconate and copper sulfate. After electrolytic oxidation of glucose to gluconic acid, it is neutralized with copper carbonate, and sorbitol is produced at the same time. It is obtained by reacting gluconic acid with copper oxide, or by reacting gluconate with copper salt, and then crystallizing. It can also be made by neutralizing gluconic acid with copper phosphate. |
category | toxic substances |
flammability hazard characteristics | combustible, the fire field discharges copper-containing spicy and stimulating smoke |
storage and transportation characteristics | warehouse low temperature, ventilation, drying |
fire extinguishing agent | water, carbon dioxide, dry powder, sand |
toxic substance data | information provided by: pubchem.ncbi.nlm.nih.gov (external link) |